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4-methyl cinnamic acid methyl ester

NMK024

Price: USD 1.00/kg
MOQ: 1000 kg

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Description

4-methyl cinnamic acid methyl ester

CAS No.: 20754-20-5

Formula: C11H12O2

Molecular Weight: 176.21

Melting point: 58～62℃

Boiling point: 273℃

Density: 1.057g/cm3

Flash point: 152℃

Refractive index : （20°C）1.5371

Molar volume: （m3/mol）153.3

Appearance: Color white to pale yellow crystalline powder

Purity:>98%

Package specification:25 kg / cardboard drum

Storage: Pay attention to the source of fire, especially to avoid sunlight, and store in a cool place.

Usage:

METHYL4-METHYLCINNAMATE is mainly used to synthesize methyl p-bromomethyl cinnamate as an upstream raw material for the antithrombotic drug Ozagrel Sodium. P-bromomethylcinnamate is brominated with N-bromosuccinimide to produce p-bromomethylcinnamate. Methyl p-bromomethylcinnamate is in ionic liquid N-n-butylpyridine tetrafluoroborate. After alkaline condensation with the imidazole in the acid salt at room temperature, the antithrombotic drug ozagrel sodium was obtained with a total yield of 67%。

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